{"aliases":[{"type":"USBrandName","name":"Celebrex"},{"type":"LexicalVariant","name":"SC 58635"},{"type":"CodeName","name":"SC-58635"},{"type":"Abbreviation","name":"SC-58635"},{"type":"ChemicalStructureName","name":"4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide"},{"type":"Synonym","name":"YM 177"},{"type":"NSCNumber","name":"719627"},{"type":"CASRegistryName","name":"169590-42-5"}],"definition":{"html":"A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.","text":"A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis."},"drugInfoSummaryLink":null,"nciConceptId":"C1728","nciConceptName":"Celecoxib","termId":43023,"name":"celecoxib","firstLetter":"c","type":"DrugTerm","termNameType":"PreferredName","prettyUrlName":"celecoxib"}