{"aliases":[{"type":"Synonym","name":"anti-IgE monoclonal antibody E25"},{"type":"CodeName","name":"IGE 025"},{"type":"Synonym","name":"olizumab"},{"type":"USBrandName","name":"Xolair"},{"type":"Abbreviation","name":"rhuMAb-E25"}],"definition":{"html":"A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E.  Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor.","text":"A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E.  Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor."},"drugInfoSummaryLink":null,"nciConceptId":null,"nciConceptName":null,"termId":699067,"name":"omalizumab","firstLetter":"o","type":"DrugTerm","termNameType":"PreferredName","prettyUrlName":"omalizumab"}