{"meta":{"totalResults":3,"from":0},"results":[{"aliases":[{"type":"ChemicalStructureName","name":"9,10-secocholesta-5,7,10(19)-trien-3-beta-ol"},{"type":"ChemicalStructureName","name":"(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol"},{"type":"ChemicalStructureName","name":"9,10-secocholesta-5,7,10(19)-trien-3-ol"},{"type":"Synonym","name":"Vitamin D3"},{"type":"Synonym","name":"Calciol"},{"type":"Synonym","name":"delsterol"},{"type":"NSCNumber","name":"375571"},{"type":"CASRegistryName","name":"67-97-0"}],"definition":{"html":"A steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption. ","text":"A steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption. "},"drugInfoSummaryLink":null,"nciConceptId":"C48194","nciConceptName":"Cholecalciferol","termId":39734,"name":"cholecalciferol","firstLetter":"c","type":"DrugTerm","termNameType":"PreferredName","prettyUrlName":"cholecalciferol"},{"aliases":[{"type":"USBrandName","name":"Prostate Health Cocktail"},{"type":"USBrandName","name":"PHC"}],"definition":{"html":"A dietary supplement consisting of a blend of 8 natural ingredients with potential antineoplastic and chemopreventive activities. This dietary supplement  contains vitamin D3 (as cholecalciferol), vitamin E (as d-alpha tocopherol), selenium (as L-selenomethionine), epigallocatechin (green tea extract), saw palmetto (berry extract), lycopene, and the isoflavonoids daidzein and genistein. This combination preparation may decrease prostate cell growth and inhibit prostate carcinogenesis.","text":"A dietary supplement consisting of a blend of 8 natural ingredients with potential antineoplastic and chemopreventive activities. This dietary supplement  contains vitamin D3 (as cholecalciferol), vitamin E (as d-alpha tocopherol), selenium (as L-selenomethionine), epigallocatechin (green tea extract), saw palmetto (berry extract), lycopene, and the isoflavonoids daidzein and genistein. This combination preparation may decrease prostate cell growth and inhibit prostate carcinogenesis."},"drugInfoSummaryLink":null,"nciConceptId":"C77860","nciConceptName":"Prostate Health Cocktail Dietary Supplement","termId":596155,"name":"cholecalciferol/d-alpha tocopherol/L-selenomethionine/green tea extract/saw palmetto berry extract/daidzein/genistein/lycopene prostate health supplement","firstLetter":"c","type":"DrugTerm","termNameType":"PreferredName","prettyUrlName":"prostate-health-cocktail-dietary-supplement"},{"aliases":[{"type":"Synonym","name":"Nutrifriend Cachexia"},{"type":"ForeignBrandName","name":"Nutrifriend 1100"}],"definition":{"html":"A gluten-free, energy-rich, non-complete nutritional supplement drink composed of juice from the concentrates of apple pear, pomegranate, purple chokeberry and passion fruit, plus fish oil derived from salmon and cod, the minerals potassium, phosphorus and iodine, whey protein isolate derived from cow’s milk, tocopherols (vitamin E), and cholecalciferol (vitamin D3) with potential anti-cachexic activity. Upon oral intake of the cholecalciferol/whey protein isolate/EPA/DHA-based nutritional supplement, the protein components maintain digestive health throughout the gastrointestinal (GI) tract and reduce the risk of digestive complications. The essential omega-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from the fish oil are incorporated into cell membranes and affect the production of pro-inflammatory mediators, which elicits an anti-inflammatory effect. Cholecalciferol plays an important role in maintaining bone mineralization and regulating blood calcium and phosphorus levels. Tocopherols neutralize free radicals, thereby protecting tissues and organs from oxidative damage. In particular, alpha-tocopherol gets incorporated into biological membranes, maintains cell membrane integrity and protects the cell against damage. This nutritional supplement may prevent both malnutrition and weight loss.","text":"A gluten-free, energy-rich, non-complete nutritional supplement drink composed of juice from the concentrates of apple pear, pomegranate, purple chokeberry and passion fruit, plus fish oil derived from salmon and cod, the minerals potassium, phosphorus and iodine, whey protein isolate derived from cow’s milk, tocopherols (vitamin E), and cholecalciferol (vitamin D3) with potential anti-cachexic activity. Upon oral intake of the cholecalciferol/whey protein isolate/EPA/DHA-based nutritional supplement, the protein components maintain digestive health throughout the gastrointestinal (GI) tract and reduce the risk of digestive complications. The essential omega-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from the fish oil are incorporated into cell membranes and affect the production of pro-inflammatory mediators, which elicits an anti-inflammatory effect. Cholecalciferol plays an important role in maintaining bone mineralization and regulating blood calcium and phosphorus levels. Tocopherols neutralize free radicals, thereby protecting tissues and organs from oxidative damage. In particular, alpha-tocopherol gets incorporated into biological membranes, maintains cell membrane integrity and protects the cell against damage. This nutritional supplement may prevent both malnutrition and weight loss."},"drugInfoSummaryLink":null,"nciConceptId":"C123916","nciConceptName":"Cholecalciferol/Whey Protein Isolate/EPA/DHA-based Nutritional Supplement","termId":775844,"name":"cholecalciferol/whey protein isolate/EPA/DHA-based nutritional supplement","firstLetter":"c","type":"DrugTerm","termNameType":"PreferredName","prettyUrlName":"cholecalciferol-whey-protein-isolate-epa-dha-based-nutritional-supplement"}],"links":null}