{"termId":460151,"language":"en","dictionary":"Cancer.gov","audience":"Patient","termName":"fluorescence in situ hybridization","firstLetter":"f","prettyUrlName":"fluorescence-in-situ-hybridization","pronunciation":{"key":"(floor-EH-sents in SY-too HY-brih-dih-ZAY-shun)","audio":"https://nci-media.cancer.gov/pdq/media/audio/716967.mp3"},"definition":{"html":"A laboratory method used to look at genes or chromosomes in cells and tissues. Pieces of DNA that contain a fluorescent dye are made in the laboratory and added to a cell or tissue sample. When these pieces of DNA bind to certain genes or areas on chromosomes in the sample, they light up when viewed under a microscope with a special light. FISH can be used to identify where a specific gene is located on a chromosome, how many copies of the gene are present, and any chromosomal abnormalities. It is used to help diagnose diseases, such as cancer, and help plan treatment. Also called FISH.","text":"A laboratory method used to look at genes or chromosomes in cells and tissues. Pieces of DNA that contain a fluorescent dye are made in the laboratory and added to a cell or tissue sample. When these pieces of DNA bind to certain genes or areas on chromosomes in the sample, they light up when viewed under a microscope with a special light. FISH can be used to identify where a specific gene is located on a chromosome, how many copies of the gene are present, and any chromosomal abnormalities. It is used to help diagnose diseases, such as cancer, and help plan treatment. Also called FISH."},"otherLanguages":[{"language":"es","termName":"hibridación fluorescente in situ","prettyUrlName":"hibridacion-fluorescente-in-situ"}],"relatedResources":[{"Type":"External","Url":"https://www.genome.gov/genetics-glossary/Fluorescence-In-Situ-Hybridization","Text":"Fluorescence In Situ Hybridization (FISH) (National Human Genome Research Institute)"}],"media":[]}